The main natural resources of the Gluboksky district, which can serve as a basis for the development of production and export potential, include land, forest, water, mineral, and recreational resources.

Land resources are characterized by hilly terrain, high stoniness, and clay soils. The Gluboksky district occupies over 175,958 sq. km: of which 88,484 (50.3%) are agricultural lands (including 51,723 arable, 36,042 meadows, 719 orchards, 24,827 improved, 11,215 natural, 3,140 under shrubs), 54,332 (30.8%) of the territory is occupied by forests, 13,016 (7.4%) by trees and shrubs, 5,306 (3%) by swamps, 3,373 (2%) by roads, 2,031 (1.5%) by buildings, 2,069 (2%) by unused lands (ravines, gullies, etc.), the total area of drained lands is 34,140 (19.4%).
To bring new lands into economic circulation, work is organized to optimize land use; part of the low-fertility arable lands with poorer characteristics is being converted into fodder and natural lands, which allows for an increase in the fodder base and the development of the production of agricultural products in demand abroad.

Currently, there has been an increase in proposals from investors to use agricultural lands for growing grain crops, vegetables, and establishing orchards and berry fields. The implementation of such proposals contributes to the development of the raw material base for the food, textile, and oil processing industries, for growing environmentally friendly products, medicinal raw materials, and their subsequent export within the investors' supply chain.

Forest resources remain among the most significant natural resources of the district: 28.1 percent of the district's land area is occupied by forests. The composition of the forests is diverse, with coniferous tree species predominating. Forest resources have relatively high productivity. The age structure of the forests is favorable for meeting the needs of the economy, both in the near and long term.

However, these resources are currently underutilized. The limited use of deep processing technologies for raw materials, primarily small-diameter timber, the predominant use of coniferous wood, the insignificant volume of hardwood processing, and the low percentage of waste production and utilization reduce export efficiency and do not ensure a more substantial inflow of foreign currency.

Most investment projects continue to be focused on exporting products with a low degree of processing. Subsequently, foreign buyers carry out final finishing of the products and resell them at prices 2-3 times higher than the export prices.

Primarily exported are pallets and pallet blanks, grape stakes, palisade timber, joinery products, edged boards, fiberboard and particleboard. The volume of exports of finished furniture blanks, furniture panels, laminated boards, various timber products, and finished construction structures is extremely low. The production of plywood, and medium and high-density wood-based panels is underdeveloped. Modern furniture production, and a wide range of furniture products for students, young people, and young families, are not developed.

Despite numerous agreements, there are few practical results in developing the production of pellets, granules, briquettes, fuel chips, various categories of firewood for domestic use, and charcoal, for which there is constant demand in the Scandinavian countries, Ireland, the United Kingdom, as well as in Lithuania, Poland, and Latvia.

The rivers of the Gluboksky district belong to the Western Dvina hydrological region. The watershed of the Baltic and Black Seas – the Western Dvina and Dnieper rivers – partially runs through the territory of the district. The total area of water protection zones is 44.7 thousand hectares, including water protection zones of small rivers – 27.5 thousand hectares. The area of coastal strips of rivers and reservoirs is 3.8 thousand hectares. In total, there are 22 small rivers in the district with a length of 379.5 km, the largest of which are Berezovka, Dobrylovka, Mnyuta, Auta (right tributaries of the Disna), Shosha, and Chistyanka. The density of the natural river network is 0.5 km/km2. The total length of the drainage network is 7.6 thousand km, including regulated water intakes of about 95 km, and main and underwater canals of 506 km.

The Glubokoye district has a total of 111 lakes and ponds (area 3347.6 ha, 3.1% of the district's area). The largest of them are Shо, Plisa, Dolgoye (the deepest lake in the Republic of Belarus), Mnyuta, Velikoye, Petrikovskoye.

A promising area for the use of water resources is the leasing of water bodies for paid amateur fishing, commercial fishing, and fish farming.

In accordance with the Republican Comprehensive Scheme for the Placement of Fishing Grounds, there are 27 reservoirs and 2 ponds available for lease in the Glubokoye district for fish farming.

The main mineral and raw resources of the district are peat, sand and gravel material, clays, sapropels, and mineral waters.

According to the State Cadastre of Mineral Reserves of the Republic of Belarus, the Glubokoye district has 2 undeveloped clay deposits in the vicinity of the village of Plisa with industrial reserves of 570 and 228 thousand m3; deposits of sand and gravel material "Pridorozhnoye" near the village of Olshchina with reserves of 811 thousand m3, "Tsegelnya" near the agro-town of Proshkovo with reserves of 441 thousand m3.

The Glubokoye district has small explored reserves of sapropels suitable for therapeutic purposes. Numerous experiments have proven that sapropel fertilizers have a positive effect on agrochemical properties, biological activity, and the content of mobile forms of nitrogen, phosphorus, potassium, and calcium in the soil. Currently, in the Vitebsk region, one sapropel deposit is being developed in the Malaya Korchinka lake of the Glubokoye district for use as therapeutic mud in the "Plissa" sanatorium.

The number of peat deposits in the district is 103, with peat reserves within the industrial depth of the peat deposit amounting to 16901 thousand tons. The "Skuraty" peat deposit is being developed by the foreign enterprise "Systemo-Dvina," and preparatory work is underway for the development of the "Kurianovo" peat deposit.